VMWare Fusion, Parallels or VirtualBox are three useful applications that allow you to virtualize Windows and run Windows applications on a Mac computer on a non-native way.
However, CrossOver alows you to run Windows applications and games on Mac in a native way without having to use an emulator. Wine is the engine of Crossovers, it's a free implementation of Windows APIs for UNIX systems.
The list of compatible applications includes the most known one, such as Microsoft Office, AutoCAD, Windows Media Player 9, Adobe Photoshop, Dreamweaver MX or Internet Explorer; as well as 3D games like Half Life 2, Call of Duty, Counter Strike or Portal. Click here to check the full list.
Insert the Cd / DVD of the program or choose the file from any drive to install it. Finally, you can choose to execute the Run Command option to run a program without having to install it.